Design, synthesis and biological evaluation of Helicobacter pylori inosine 5′-monophosphate dehydrogenase (HpIMPDH) inhibitors

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A collaborative research article titled ‘Design, synthesis and biological evaluation of Helicobacter pylori inosine 5′-monophosphate dehydrogenase (HpIMPDH) inhibitors. Further optimization of selectivity towards HpIMPDH over human IMPDH2′ authored by Chetan P. Shah, Gayathri Purushothaman, Vijay Thiruvenkatam, Sivapriya Kirubakaran, Kapil Juvale and Prashant S. Kharkar has been published in ‘Bioorganic Chemistry’, Elsevier, 2019, Vol 87, 753-764.
This is an outcome of research work carried out in collaboration with team of Dr. Sivapriya Kirubakaran and Dr. Vijay Thiruvenkatam IIT Gandhinagar.
The impact factor of the journal is 3.929 (Clarivate Analytics).
We congratulate Dr. Kapil Juvale, Dr. Prashant Kharkar and co-authors for this achievement !

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